Colección: Ultracentrífugas
Ultracentrífugas a la venta - Nuevas y reacondicionadas | mLab Supply
Las ultracentrífugas operan a velocidades superiores a 50.000 RPM y generan fuerzas que exceden 100.000 x g para fraccionamiento subcelular, separaciones por gradiente de densidad y sedimentación macromolecular. mLab Supply comercializa ultracentrífugas preparativas y analíticas nuevas, reacondicionadas y excedentes de los principales fabricantes.
Equipo de centrífuga relacionado
- Centrífugas - Centrífugas de sobremesa y de pie de uso general
- Centrífugas refrigeradas - Centrifugación con temperatura controlada para muestras sensibles
- Microcentrífugas - Microcentrífugas de alta velocidad para tubos de 0,5-2,0 mL
Casos de uso comunes
- Fraccionamiento subcelular y aislamiento de orgánulos
- Separaciones por gradiente de densidad (sacarosa, CsCl, iodixanol)
- Purificación y concentración de virus y vectores virales
- Aislamiento de lipoproteínas y exosomas
- Sedimentación macromolecular de ribosomas y grandes complejos proteicos
Qué buscar
- Velocidad máxima y RCF: Confirme la velocidad y la fuerza g requeridas para su aplicación; el aislamiento de exosomas suele requerir 100.000-200.000 x g
- Compatibilidad de rotor: Confirme la disponibilidad de rotores de balancín, de ángulo fijo y verticales para los tamaños y volúmenes de sus tubos
- Refrigeración: Todas las ultracentrífugas preparativas incluyen refrigeración; confirme el rango y la estabilidad de la temperatura
- Certificación del rotor: Los rotores tienen límites de horas de funcionamiento definidos; confirme la antigüedad y el estado de certificación del rotor antes de la compra
Marcas que comercializamos
Beckman Coulter (Optima XPN, serie L, Avanti J) | Thermo Fisher (Sorvall WX, Discovery 100) | Hitachi
Opciones de condición
- Nuevas (modelos seleccionados disponibles para comercializar)
- Reacondicionadas / Usadas - rotor inspeccionado, velocidad verificada y sistema de vacío probado
- Excedente / Tal cual - precio acorde
La disponibilidad y los precios están sujetos a cambios. Envíe una solicitud de presupuesto y confirmaremos el stock actual, el plazo de entrega y la disponibilidad del rotor en 1-2 días hábiles.
-
Hitachi CP100NX Ultracentrifuge — Request a Quote
Request Pricing
Agotado -
Thermo Scientific Sorvall WX+ Ultracentrifuge — Request a Quote
Request Pricing
Agotado -
Beckman Coulter Optima L-90K Ultracentrifuge — Request a Quote
Request Pricing
Agotado -
Beckman Coulter Optima XE-90 Ultracentrifuge — Request a Quote
Request Pricing
Agotado
<h2>How to Choose an Ultracentrifuge</h2>
<p>Selecting an ultracentrifuge requires evaluating several technical and operational factors beyond maximum speed. Understanding these considerations before sourcing a used or refurbished unit helps ensure the instrument fits your workflow without requiring costly modifications or infrastructure changes.</p>
<ul>
<li><strong>Floor-standing vs. benchtop:</strong> Floor-standing ultracentrifuges such as the Beckman Coulter Optima XPN and Optima XE-90 offer higher capacity, broader rotor compatibility, and higher maximum speeds. Benchtop ultracentrifuges such as the Beckman Coulter Optima MAX-XP are compact, require less floor space, and are suited to smaller sample volumes and microvolume applications. Confirm which format fits your available bench or floor space and electrical infrastructure before sourcing.</li>
<li><strong>Maximum speed and RCF:</strong> Ultracentrifuges are defined by their ability to reach speeds typically above 50,000 RPM and generate RCF values exceeding 100,000 × g. Confirm the maximum rated speed of the instrument and the maximum rated speed of any rotor you intend to use. Rotor-rated speed may be lower than instrument-rated speed.</li>
<li><strong>Rotor compatibility:</strong> Rotors are not universally interchangeable. Confirm that the rotors you intend to use are compatible with the specific instrument model and drive head. Rotor availability, condition, and age are separate considerations from the instrument itself.</li>
<li><strong>Sample throughput:</strong> Consider the number of tubes or bottles per run, total sample volume per run, and how many runs per day your workflow requires. Floor-standing systems generally support larger rotor capacities and higher throughput than benchtop systems.</li>
<li><strong>Refrigeration:</strong> Most ultracentrifuges include an integrated refrigeration system to maintain sample temperature during high-speed runs. Confirm the refrigeration system is functional and that the instrument can maintain the required temperature range for your application.</li>
<li><strong>Vacuum system:</strong> Ultracentrifuges operate under vacuum to reduce aerodynamic drag and heat generation at high speeds. Confirm the vacuum system achieves and maintains the required vacuum level. Vacuum pump condition and seal integrity are important inspection points on used instruments.</li>
<li><strong>Power and installation requirements:</strong> Floor-standing ultracentrifuges typically require dedicated electrical circuits, specific voltage and amperage, and may require facility modifications. Confirm power requirements before sourcing and coordinate with your facilities team for installation planning.</li>
<li><strong>Laboratory workflow:</strong> Consider whether the instrument needs to integrate with a LIMS, support regulated workflows, or fit within a quality system. For regulated applications, confirm what documentation and qualification support is available for the sourced unit.</li>
</ul>
<h2>Ultracentrifuge Types</h2>
<h3>Floor-Standing Ultracentrifuges</h3>
<p>Floor-standing ultracentrifuges are large, high-capacity instruments designed for demanding separation workflows. They support a broad range of rotor types and sizes, accommodate larger sample volumes, and typically reach higher maximum speeds than benchtop systems. Floor-standing ultracentrifuges require dedicated floor space, appropriate electrical infrastructure, and in some cases facility modifications for installation. Common floor-standing models include the Beckman Coulter Optima XPN series, Optima XE-90, Optima L-90K, and the Thermo Scientific Sorvall WX+. These systems are widely used in pharmaceutical manufacturing, bioprocess development, virology, and high-throughput research environments.</p>
<h3>Benchtop Ultracentrifuges</h3>
<p>Benchtop ultracentrifuges are compact instruments designed for microvolume and small-scale ultracentrifugation applications. They fit on a standard laboratory bench, require standard electrical connections, and are easier to install and relocate than floor-standing systems. Benchtop ultracentrifuges support a more limited range of rotor types and smaller sample volumes. Common benchtop models include the Beckman Coulter Optima MAX-XP and the Hitachi CP100NX. These systems are well suited to academic research, analytical ultracentrifugation, and applications requiring small sample volumes such as exosome isolation and lipoprotein analysis.</p>
<h2>Popular Ultracentrifuge Manufacturers and Models</h2>
<p>mLab Supply sources ultracentrifuges from leading manufacturers including Beckman Coulter, Thermo Scientific, and Hitachi. Common models available to source include:</p>
<ul class="mlab-collection-model-grid">
<li>Beckman Coulter Optima XPN</li>
<li>Beckman Coulter Optima XE-90</li>
<li>Beckman Coulter Optima L-90K</li>
<li>Beckman Coulter Optima MAX-XP</li>
<li>Thermo Scientific Sorvall WX+</li>
<li>Hitachi CP100NX</li>
</ul>
<p>Model availability varies. Submit a quote request to confirm current sourcing options for a specific model or configuration.</p>
<h2>Rotors and Compatibility</h2>
<p>Rotors are a critical component of any ultracentrifuge system and must be evaluated separately from the instrument itself.</p>
<ul>
<li><strong>Fixed-angle rotors:</strong> Fixed-angle rotors hold tubes at a fixed angle relative to the axis of rotation. They are commonly used for pelleting applications, density-gradient separations, and general high-speed separations. Fixed-angle rotors are the most widely available rotor type on the secondary market.</li>
<li><strong>Swinging-bucket rotors:</strong> Swinging-bucket rotors allow tubes to swing outward to a horizontal position during centrifugation. They are used for rate-zonal separations, gradient fractionation, and applications where maintaining a sharp band or gradient interface is important.</li>
<li><strong>Vertical and near-vertical rotors:</strong> Vertical and near-vertical rotors orient tubes parallel or nearly parallel to the axis of rotation. They are used for isopycnic separations and applications requiring short run times with high resolution.</li>
<li><strong>Rotor model compatibility:</strong> Rotors are not universally interchangeable between instrument models or manufacturers. Confirm rotor compatibility with the specific instrument model before sourcing. Rotor adapters may be available for some configurations.</li>
<li><strong>Maximum rotor-rated speed:</strong> Each rotor has its own maximum rated speed, which may be lower than the instrument's maximum rated speed. Always operate rotors within their rated speed limits.</li>
<li><strong>Rotor age and condition:</strong> Rotor age, run history, and condition are important safety and performance considerations. Inspect rotors for corrosion, cracks, pitting, or damage to the rotor body, tube holes, and drive hub. Request rotor run logs or service history where available.</li>
<li><strong>Tube and bottle compatibility:</strong> Confirm that the rotor is compatible with the tube or bottle format, material, and volume required for your application. Adapters may be required for some tube sizes.</li>
</ul>
<p><strong>Important:</strong> Sourced ultracentrifuges are not guaranteed to include a rotor. Rotor inclusion varies by listing. Confirm rotor availability and condition when requesting a quote.</p>
<h2>Buying Used and Refurbished Ultracentrifuges</h2>
<p>Used and refurbished ultracentrifuges represent a cost-effective option for many laboratory applications. When evaluating a sourced unit, consider the following:</p>
<ul>
<li><strong>Chamber condition:</strong> Inspect the centrifuge chamber for corrosion, contamination, or damage. Chamber condition affects both safety and performance.</li>
<li><strong>Vacuum performance:</strong> Confirm the vacuum system achieves and holds the required vacuum level. Vacuum pump condition, seal integrity, and O-ring condition are key inspection points.</li>
<li><strong>Refrigeration system:</strong> Confirm the refrigeration system cools to the required temperature range and maintains temperature stability during operation.</li>
<li><strong>Lid locking mechanism:</strong> Confirm the lid locking mechanism engages and releases correctly. A properly functioning lid lock is a critical safety feature.</li>
<li><strong>Rotor drive condition:</strong> Inspect the rotor drive spindle for wear, damage, or corrosion. Drive condition affects rotor seating and safe operation at high speeds.</li>
<li><strong>Controller and display:</strong> Confirm the control panel, display, and programming interface are functional. Verify that speed, time, temperature, and acceleration/deceleration settings operate correctly.</li>
<li><strong>Service history:</strong> Where available, review preventive maintenance records and any prior repair documentation. Service history is particularly important for high-speed instruments.</li>
<li><strong>Included rotor and accessories:</strong> Confirm which rotors, adapters, and accessories are included with the sourced unit. Rotors and accessories are often sold separately and add significant cost.</li>
<li><strong>Software and firmware:</strong> For instruments with PC-based control or data logging, confirm software availability and version compatibility.</li>
<li><strong>Voltage and installation:</strong> Verify voltage, amperage, and phase requirements. Floor-standing ultracentrifuges often require dedicated circuits and may require facility modifications. Confirm compatibility with your facility before sourcing.</li>
</ul>
<p>Configuration, condition, included accessories, and available documentation vary by sourced unit. mLab Supply is not an authorized dealer for any ultracentrifuge manufacturer.</p>
<h2>Applications</h2>
<p>Ultracentrifuges support a broad range of high-speed separation and analytical workflows, including:</p>
<ul>
<li>Virus and viral vector concentration and purification</li>
<li>Extracellular vesicle and exosome isolation</li>
<li>Protein and macromolecule separation and purification</li>
<li>Density-gradient centrifugation (sucrose, CsCl, iodixanol gradients)</li>
<li>Nucleic acid isolation and pelleting</li>
<li>Subcellular fractionation and organelle isolation</li>
<li>Lipoprotein separation and analysis</li>
<li>Bioprocess development and upstream/downstream processing research</li>
<li>Academic and pharmaceutical research applications</li>
</ul>
<p>Claims about specific application suitability depend on instrument configuration, rotor selection, and laboratory protocol. Confirm instrument and rotor specifications against your application requirements before sourcing.</p>
<h2>Ultracentrifuges vs. Standard Centrifuges</h2>
<p>Ultracentrifuges are a distinct instrument category from standard laboratory centrifuges and high-speed centrifuges, and are not interchangeable for most applications.</p>
<ul>
<li><strong>Standard laboratory centrifuges</strong> typically operate up to approximately 6,000–10,000 RPM and generate RCF values up to roughly 10,000–15,000 × g. They are used for routine sample preparation, cell pelleting, and general separation workflows.</li>
<li><strong>High-speed centrifuges</strong> operate in the range of approximately 20,000–30,000 RPM and generate RCF values up to roughly 70,000–100,000 × g. They are used for bacterial cell pelleting, mitochondrial isolation, and other applications requiring higher speeds than standard centrifuges.</li>
<li><strong>Ultracentrifuges</strong> operate above approximately 50,000 RPM and generate RCF values exceeding 100,000 × g, with some systems reaching 800,000 × g or higher. They are required for applications such as virus pelleting, exosome isolation, and macromolecule separation that cannot be achieved at lower speeds.</li>
</ul>
<p>If your application does not require ultracentrifuge speeds, a standard or high-speed centrifuge may be more appropriate. See our <a href="/collections/centrifuges">Centrifuges</a> collection for standard and high-speed centrifuge options.</p>
<h2>Procurement Support</h2>
<p>mLab Supply supports institutional and organizational purchasing for ultracentrifuges and related laboratory equipment. Our sourcing team can assist with:</p>
<ul>
<li>Formal written quotations for procurement and budget approval</li>
<li>Institutional purchase order processing</li>
<li>Vendor onboarding and supplier documentation</li>
<li>Net 30 payment terms for qualified organizations — see our <a href="/pages/net-30-credit-terms">Net 30 Credit Terms</a> page for details</li>
<li>Sourcing specific models, configurations, and rotor combinations on request</li>
<li>Multi-unit sourcing for core facilities and larger laboratory buildouts</li>
<li>Freight and logistics coordination for floor-standing ultracentrifuge systems — floor-standing units are large, heavy instruments that require freight shipping and may require liftgate, inside delivery, or rigging services. Confirm freight requirements and site access when requesting a quote.</li>
</ul>
<p>To initiate a quote or discuss procurement requirements, use our <a href="/pages/request-a-quote">Request a Quote</a> form.</p>
<h2>Related Laboratory Equipment</h2>
<p>Ultracentrifuges are commonly used alongside other separation, storage, and analytical instruments. Related equipment available to source from mLab Supply includes <a href="/collections/centrifuges">Centrifuges</a> for standard and high-speed separation workflows, <a href="/collections/ultra-low-temperature-freezers">Ultra-Low Temperature Freezers</a> for long-term sample storage following ultracentrifugation, and <a href="/collections/flow-cytometers">Flow Cytometers</a> for downstream analysis of isolated cell populations and vesicles. Browse our full <a href="/collections/labequipment">laboratory equipment catalog</a> or visit our manufacturer pages for <a href="/collections/beckman-coulter">Beckman Coulter Laboratory Equipment</a> and <a href="/collections/thermo-scientific">Thermo Scientific Laboratory Equipment</a>. To discuss sourcing requirements, use our <a href="/pages/request-a-quote">Request a Quote</a> form.</p>
<h2>Frequently Asked Questions</h2>
<div class="mlab-collection-faq">
<details>
<summary>What is the difference between an ultracentrifuge and a standard centrifuge?</summary>
<div class="mlab-collection-faq__answer">
<p>Standard laboratory centrifuges typically operate up to approximately 10,000 RPM and generate RCF values up to roughly 15,000 × g. Ultracentrifuges operate above approximately 50,000 RPM and generate RCF values exceeding 100,000 × g — with some systems reaching 800,000 × g or higher. This speed range is required for applications such as virus pelleting, exosome isolation, protein sedimentation, and density-gradient separations that cannot be achieved with standard or high-speed centrifuges. If your application does not require ultracentrifuge speeds, a standard centrifuge is likely more appropriate and significantly less expensive to source and operate.</p>
</div>
</details>
<details>
<summary>What RCF do I need for my application?</summary>
<div class="mlab-collection-faq__answer">
<p>Required RCF depends on your specific application and protocol. As general reference points: exosome and extracellular vesicle isolation typically requires 100,000–200,000 × g; virus pelleting typically requires 100,000–150,000 × g; lipoprotein separation typically requires 100,000–400,000 × g; and analytical ultracentrifugation may require up to 800,000 × g. Consult your protocol or published literature for the specific RCF and run time required for your application. Confirm that the instrument and rotor combination you source can achieve the required RCF.</p>
</div>
</details>
<details>
<summary>Does an ultracentrifuge include a rotor?</summary>
<div class="mlab-collection-faq__answer">
<p>Not necessarily. Rotor inclusion varies by sourced unit. Some listings include one or more rotors; others are instrument-only. Rotors are high-value components and are often sold separately. When requesting a quote, specify which rotor type and format you require so our sourcing team can confirm availability and condition for the specific unit.</p>
</div>
</details>
<details>
<summary>How do I verify rotor compatibility?</summary>
<div class="mlab-collection-faq__answer">
<p>Rotor compatibility depends on the specific instrument model and drive head. Rotors are not universally interchangeable between models or manufacturers. To verify compatibility, cross-reference the rotor model number against the instrument manufacturer's rotor compatibility list for that specific instrument model. When requesting a quote, provide the rotor model numbers you intend to use and our sourcing team will confirm compatibility with the available instrument.</p>
</div>
</details>
<details>
<summary>What should I inspect on a used ultracentrifuge?</summary>
<div class="mlab-collection-faq__answer">
<p>Key inspection points include: chamber condition (corrosion, contamination, damage); vacuum system performance (pump condition, seal integrity, achieved vacuum level); refrigeration system function and temperature stability; lid locking mechanism engagement and release; rotor drive spindle condition; controller and display functionality; service and maintenance history; included rotors and accessories; software or firmware availability where applicable; and power requirements and voltage compatibility. For regulated laboratory applications, confirm what qualification documentation is available or can be generated for the sourced unit.</p>
</div>
</details>
<details>
<summary>Can mLab Supply source a specific Beckman Coulter Optima model?</summary>
<div class="mlab-collection-faq__answer">
<p>Yes. If a specific Optima model or configuration is not currently listed, submit a quote request with the model name, rotor requirements, and any other specifications. Our sourcing team will search our supplier and secondary-market network and respond with available options, lead time estimates, and pricing. We source Optima XPN, Optima XE-90, Optima L-90K, Optima MAX-XP, and other Beckman Coulter ultracentrifuge models.</p>
</div>
</details>
<details>
<summary>Are refurbished ultracentrifuges suitable for regulated laboratories?</summary>
<div class="mlab-collection-faq__answer">
<p>Suitability for regulated use depends on your organization's quality system requirements, SOPs, validation protocols, and documentation standards — not solely on the instrument's refurbishment status. Some regulated laboratories successfully qualify and use refurbished ultracentrifuges after completing IQ/OQ/PQ protocols with appropriate documentation. Others require new instruments with full manufacturer documentation. Consult your quality assurance team to determine what documentation, calibration records, and qualification steps are required before sourcing a used unit for regulated applications. mLab Supply does not make representations about GMP or clinical suitability for any sourced instrument.</p>
</div>
</details>
<details>
<summary>What power requirements should I confirm before sourcing a floor-standing ultracentrifuge?</summary>
<div class="mlab-collection-faq__answer">
<p>Floor-standing ultracentrifuges typically require dedicated electrical circuits with specific voltage (commonly 208V or 230V single- or three-phase), amperage, and outlet configurations that differ from standard laboratory outlets. Confirm the instrument's voltage, amperage, phase, and outlet requirements before sourcing, and coordinate with your facilities team to verify that your laboratory can support the required electrical infrastructure. Failure to confirm power requirements before delivery can result in significant installation delays and additional cost.</p>
</div>
</details>
<details>
<summary>Does mLab Supply coordinate freight for floor-standing ultracentrifuges?</summary>
<div class="mlab-collection-faq__answer">
<p>Yes. Floor-standing ultracentrifuges are large, heavy instruments that require freight shipping rather than standard parcel delivery. mLab Supply can coordinate freight logistics for floor-standing systems. Freight requirements vary by instrument and destination, and may include liftgate service, inside delivery, or rigging depending on your facility. Confirm site access, loading dock availability, and any special delivery requirements when requesting a quote so we can provide accurate freight information.</p>
</div>
</details>
<details>
<summary>Does mLab Supply purchase surplus ultracentrifuges?</summary>
<div class="mlab-collection-faq__answer">
<p>Yes. mLab Supply purchases surplus and used laboratory equipment including ultracentrifuges. If your organization is decommissioning ultracentrifuge systems, contact us through the <a href="/pages/request-a-quote">Request a Quote</a> page to discuss equipment valuation and purchasing options.</p>
</div>
</details>
</div>
<p>Selecting an ultracentrifuge requires evaluating several technical and operational factors beyond maximum speed. Understanding these considerations before sourcing a used or refurbished unit helps ensure the instrument fits your workflow without requiring costly modifications or infrastructure changes.</p>
<ul>
<li><strong>Floor-standing vs. benchtop:</strong> Floor-standing ultracentrifuges such as the Beckman Coulter Optima XPN and Optima XE-90 offer higher capacity, broader rotor compatibility, and higher maximum speeds. Benchtop ultracentrifuges such as the Beckman Coulter Optima MAX-XP are compact, require less floor space, and are suited to smaller sample volumes and microvolume applications. Confirm which format fits your available bench or floor space and electrical infrastructure before sourcing.</li>
<li><strong>Maximum speed and RCF:</strong> Ultracentrifuges are defined by their ability to reach speeds typically above 50,000 RPM and generate RCF values exceeding 100,000 × g. Confirm the maximum rated speed of the instrument and the maximum rated speed of any rotor you intend to use. Rotor-rated speed may be lower than instrument-rated speed.</li>
<li><strong>Rotor compatibility:</strong> Rotors are not universally interchangeable. Confirm that the rotors you intend to use are compatible with the specific instrument model and drive head. Rotor availability, condition, and age are separate considerations from the instrument itself.</li>
<li><strong>Sample throughput:</strong> Consider the number of tubes or bottles per run, total sample volume per run, and how many runs per day your workflow requires. Floor-standing systems generally support larger rotor capacities and higher throughput than benchtop systems.</li>
<li><strong>Refrigeration:</strong> Most ultracentrifuges include an integrated refrigeration system to maintain sample temperature during high-speed runs. Confirm the refrigeration system is functional and that the instrument can maintain the required temperature range for your application.</li>
<li><strong>Vacuum system:</strong> Ultracentrifuges operate under vacuum to reduce aerodynamic drag and heat generation at high speeds. Confirm the vacuum system achieves and maintains the required vacuum level. Vacuum pump condition and seal integrity are important inspection points on used instruments.</li>
<li><strong>Power and installation requirements:</strong> Floor-standing ultracentrifuges typically require dedicated electrical circuits, specific voltage and amperage, and may require facility modifications. Confirm power requirements before sourcing and coordinate with your facilities team for installation planning.</li>
<li><strong>Laboratory workflow:</strong> Consider whether the instrument needs to integrate with a LIMS, support regulated workflows, or fit within a quality system. For regulated applications, confirm what documentation and qualification support is available for the sourced unit.</li>
</ul>
<h2>Ultracentrifuge Types</h2>
<h3>Floor-Standing Ultracentrifuges</h3>
<p>Floor-standing ultracentrifuges are large, high-capacity instruments designed for demanding separation workflows. They support a broad range of rotor types and sizes, accommodate larger sample volumes, and typically reach higher maximum speeds than benchtop systems. Floor-standing ultracentrifuges require dedicated floor space, appropriate electrical infrastructure, and in some cases facility modifications for installation. Common floor-standing models include the Beckman Coulter Optima XPN series, Optima XE-90, Optima L-90K, and the Thermo Scientific Sorvall WX+. These systems are widely used in pharmaceutical manufacturing, bioprocess development, virology, and high-throughput research environments.</p>
<h3>Benchtop Ultracentrifuges</h3>
<p>Benchtop ultracentrifuges are compact instruments designed for microvolume and small-scale ultracentrifugation applications. They fit on a standard laboratory bench, require standard electrical connections, and are easier to install and relocate than floor-standing systems. Benchtop ultracentrifuges support a more limited range of rotor types and smaller sample volumes. Common benchtop models include the Beckman Coulter Optima MAX-XP and the Hitachi CP100NX. These systems are well suited to academic research, analytical ultracentrifugation, and applications requiring small sample volumes such as exosome isolation and lipoprotein analysis.</p>
<h2>Popular Ultracentrifuge Manufacturers and Models</h2>
<p>mLab Supply sources ultracentrifuges from leading manufacturers including Beckman Coulter, Thermo Scientific, and Hitachi. Common models available to source include:</p>
<ul class="mlab-collection-model-grid">
<li>Beckman Coulter Optima XPN</li>
<li>Beckman Coulter Optima XE-90</li>
<li>Beckman Coulter Optima L-90K</li>
<li>Beckman Coulter Optima MAX-XP</li>
<li>Thermo Scientific Sorvall WX+</li>
<li>Hitachi CP100NX</li>
</ul>
<p>Model availability varies. Submit a quote request to confirm current sourcing options for a specific model or configuration.</p>
<h2>Rotors and Compatibility</h2>
<p>Rotors are a critical component of any ultracentrifuge system and must be evaluated separately from the instrument itself.</p>
<ul>
<li><strong>Fixed-angle rotors:</strong> Fixed-angle rotors hold tubes at a fixed angle relative to the axis of rotation. They are commonly used for pelleting applications, density-gradient separations, and general high-speed separations. Fixed-angle rotors are the most widely available rotor type on the secondary market.</li>
<li><strong>Swinging-bucket rotors:</strong> Swinging-bucket rotors allow tubes to swing outward to a horizontal position during centrifugation. They are used for rate-zonal separations, gradient fractionation, and applications where maintaining a sharp band or gradient interface is important.</li>
<li><strong>Vertical and near-vertical rotors:</strong> Vertical and near-vertical rotors orient tubes parallel or nearly parallel to the axis of rotation. They are used for isopycnic separations and applications requiring short run times with high resolution.</li>
<li><strong>Rotor model compatibility:</strong> Rotors are not universally interchangeable between instrument models or manufacturers. Confirm rotor compatibility with the specific instrument model before sourcing. Rotor adapters may be available for some configurations.</li>
<li><strong>Maximum rotor-rated speed:</strong> Each rotor has its own maximum rated speed, which may be lower than the instrument's maximum rated speed. Always operate rotors within their rated speed limits.</li>
<li><strong>Rotor age and condition:</strong> Rotor age, run history, and condition are important safety and performance considerations. Inspect rotors for corrosion, cracks, pitting, or damage to the rotor body, tube holes, and drive hub. Request rotor run logs or service history where available.</li>
<li><strong>Tube and bottle compatibility:</strong> Confirm that the rotor is compatible with the tube or bottle format, material, and volume required for your application. Adapters may be required for some tube sizes.</li>
</ul>
<p><strong>Important:</strong> Sourced ultracentrifuges are not guaranteed to include a rotor. Rotor inclusion varies by listing. Confirm rotor availability and condition when requesting a quote.</p>
<h2>Buying Used and Refurbished Ultracentrifuges</h2>
<p>Used and refurbished ultracentrifuges represent a cost-effective option for many laboratory applications. When evaluating a sourced unit, consider the following:</p>
<ul>
<li><strong>Chamber condition:</strong> Inspect the centrifuge chamber for corrosion, contamination, or damage. Chamber condition affects both safety and performance.</li>
<li><strong>Vacuum performance:</strong> Confirm the vacuum system achieves and holds the required vacuum level. Vacuum pump condition, seal integrity, and O-ring condition are key inspection points.</li>
<li><strong>Refrigeration system:</strong> Confirm the refrigeration system cools to the required temperature range and maintains temperature stability during operation.</li>
<li><strong>Lid locking mechanism:</strong> Confirm the lid locking mechanism engages and releases correctly. A properly functioning lid lock is a critical safety feature.</li>
<li><strong>Rotor drive condition:</strong> Inspect the rotor drive spindle for wear, damage, or corrosion. Drive condition affects rotor seating and safe operation at high speeds.</li>
<li><strong>Controller and display:</strong> Confirm the control panel, display, and programming interface are functional. Verify that speed, time, temperature, and acceleration/deceleration settings operate correctly.</li>
<li><strong>Service history:</strong> Where available, review preventive maintenance records and any prior repair documentation. Service history is particularly important for high-speed instruments.</li>
<li><strong>Included rotor and accessories:</strong> Confirm which rotors, adapters, and accessories are included with the sourced unit. Rotors and accessories are often sold separately and add significant cost.</li>
<li><strong>Software and firmware:</strong> For instruments with PC-based control or data logging, confirm software availability and version compatibility.</li>
<li><strong>Voltage and installation:</strong> Verify voltage, amperage, and phase requirements. Floor-standing ultracentrifuges often require dedicated circuits and may require facility modifications. Confirm compatibility with your facility before sourcing.</li>
</ul>
<p>Configuration, condition, included accessories, and available documentation vary by sourced unit. mLab Supply is not an authorized dealer for any ultracentrifuge manufacturer.</p>
<h2>Applications</h2>
<p>Ultracentrifuges support a broad range of high-speed separation and analytical workflows, including:</p>
<ul>
<li>Virus and viral vector concentration and purification</li>
<li>Extracellular vesicle and exosome isolation</li>
<li>Protein and macromolecule separation and purification</li>
<li>Density-gradient centrifugation (sucrose, CsCl, iodixanol gradients)</li>
<li>Nucleic acid isolation and pelleting</li>
<li>Subcellular fractionation and organelle isolation</li>
<li>Lipoprotein separation and analysis</li>
<li>Bioprocess development and upstream/downstream processing research</li>
<li>Academic and pharmaceutical research applications</li>
</ul>
<p>Claims about specific application suitability depend on instrument configuration, rotor selection, and laboratory protocol. Confirm instrument and rotor specifications against your application requirements before sourcing.</p>
<h2>Ultracentrifuges vs. Standard Centrifuges</h2>
<p>Ultracentrifuges are a distinct instrument category from standard laboratory centrifuges and high-speed centrifuges, and are not interchangeable for most applications.</p>
<ul>
<li><strong>Standard laboratory centrifuges</strong> typically operate up to approximately 6,000–10,000 RPM and generate RCF values up to roughly 10,000–15,000 × g. They are used for routine sample preparation, cell pelleting, and general separation workflows.</li>
<li><strong>High-speed centrifuges</strong> operate in the range of approximately 20,000–30,000 RPM and generate RCF values up to roughly 70,000–100,000 × g. They are used for bacterial cell pelleting, mitochondrial isolation, and other applications requiring higher speeds than standard centrifuges.</li>
<li><strong>Ultracentrifuges</strong> operate above approximately 50,000 RPM and generate RCF values exceeding 100,000 × g, with some systems reaching 800,000 × g or higher. They are required for applications such as virus pelleting, exosome isolation, and macromolecule separation that cannot be achieved at lower speeds.</li>
</ul>
<p>If your application does not require ultracentrifuge speeds, a standard or high-speed centrifuge may be more appropriate. See our <a href="/collections/centrifuges">Centrifuges</a> collection for standard and high-speed centrifuge options.</p>
<h2>Procurement Support</h2>
<p>mLab Supply supports institutional and organizational purchasing for ultracentrifuges and related laboratory equipment. Our sourcing team can assist with:</p>
<ul>
<li>Formal written quotations for procurement and budget approval</li>
<li>Institutional purchase order processing</li>
<li>Vendor onboarding and supplier documentation</li>
<li>Net 30 payment terms for qualified organizations — see our <a href="/pages/net-30-credit-terms">Net 30 Credit Terms</a> page for details</li>
<li>Sourcing specific models, configurations, and rotor combinations on request</li>
<li>Multi-unit sourcing for core facilities and larger laboratory buildouts</li>
<li>Freight and logistics coordination for floor-standing ultracentrifuge systems — floor-standing units are large, heavy instruments that require freight shipping and may require liftgate, inside delivery, or rigging services. Confirm freight requirements and site access when requesting a quote.</li>
</ul>
<p>To initiate a quote or discuss procurement requirements, use our <a href="/pages/request-a-quote">Request a Quote</a> form.</p>
<h2>Related Laboratory Equipment</h2>
<p>Ultracentrifuges are commonly used alongside other separation, storage, and analytical instruments. Related equipment available to source from mLab Supply includes <a href="/collections/centrifuges">Centrifuges</a> for standard and high-speed separation workflows, <a href="/collections/ultra-low-temperature-freezers">Ultra-Low Temperature Freezers</a> for long-term sample storage following ultracentrifugation, and <a href="/collections/flow-cytometers">Flow Cytometers</a> for downstream analysis of isolated cell populations and vesicles. Browse our full <a href="/collections/labequipment">laboratory equipment catalog</a> or visit our manufacturer pages for <a href="/collections/beckman-coulter">Beckman Coulter Laboratory Equipment</a> and <a href="/collections/thermo-scientific">Thermo Scientific Laboratory Equipment</a>. To discuss sourcing requirements, use our <a href="/pages/request-a-quote">Request a Quote</a> form.</p>
<h2>Frequently Asked Questions</h2>
<div class="mlab-collection-faq">
<details>
<summary>What is the difference between an ultracentrifuge and a standard centrifuge?</summary>
<div class="mlab-collection-faq__answer">
<p>Standard laboratory centrifuges typically operate up to approximately 10,000 RPM and generate RCF values up to roughly 15,000 × g. Ultracentrifuges operate above approximately 50,000 RPM and generate RCF values exceeding 100,000 × g — with some systems reaching 800,000 × g or higher. This speed range is required for applications such as virus pelleting, exosome isolation, protein sedimentation, and density-gradient separations that cannot be achieved with standard or high-speed centrifuges. If your application does not require ultracentrifuge speeds, a standard centrifuge is likely more appropriate and significantly less expensive to source and operate.</p>
</div>
</details>
<details>
<summary>What RCF do I need for my application?</summary>
<div class="mlab-collection-faq__answer">
<p>Required RCF depends on your specific application and protocol. As general reference points: exosome and extracellular vesicle isolation typically requires 100,000–200,000 × g; virus pelleting typically requires 100,000–150,000 × g; lipoprotein separation typically requires 100,000–400,000 × g; and analytical ultracentrifugation may require up to 800,000 × g. Consult your protocol or published literature for the specific RCF and run time required for your application. Confirm that the instrument and rotor combination you source can achieve the required RCF.</p>
</div>
</details>
<details>
<summary>Does an ultracentrifuge include a rotor?</summary>
<div class="mlab-collection-faq__answer">
<p>Not necessarily. Rotor inclusion varies by sourced unit. Some listings include one or more rotors; others are instrument-only. Rotors are high-value components and are often sold separately. When requesting a quote, specify which rotor type and format you require so our sourcing team can confirm availability and condition for the specific unit.</p>
</div>
</details>
<details>
<summary>How do I verify rotor compatibility?</summary>
<div class="mlab-collection-faq__answer">
<p>Rotor compatibility depends on the specific instrument model and drive head. Rotors are not universally interchangeable between models or manufacturers. To verify compatibility, cross-reference the rotor model number against the instrument manufacturer's rotor compatibility list for that specific instrument model. When requesting a quote, provide the rotor model numbers you intend to use and our sourcing team will confirm compatibility with the available instrument.</p>
</div>
</details>
<details>
<summary>What should I inspect on a used ultracentrifuge?</summary>
<div class="mlab-collection-faq__answer">
<p>Key inspection points include: chamber condition (corrosion, contamination, damage); vacuum system performance (pump condition, seal integrity, achieved vacuum level); refrigeration system function and temperature stability; lid locking mechanism engagement and release; rotor drive spindle condition; controller and display functionality; service and maintenance history; included rotors and accessories; software or firmware availability where applicable; and power requirements and voltage compatibility. For regulated laboratory applications, confirm what qualification documentation is available or can be generated for the sourced unit.</p>
</div>
</details>
<details>
<summary>Can mLab Supply source a specific Beckman Coulter Optima model?</summary>
<div class="mlab-collection-faq__answer">
<p>Yes. If a specific Optima model or configuration is not currently listed, submit a quote request with the model name, rotor requirements, and any other specifications. Our sourcing team will search our supplier and secondary-market network and respond with available options, lead time estimates, and pricing. We source Optima XPN, Optima XE-90, Optima L-90K, Optima MAX-XP, and other Beckman Coulter ultracentrifuge models.</p>
</div>
</details>
<details>
<summary>Are refurbished ultracentrifuges suitable for regulated laboratories?</summary>
<div class="mlab-collection-faq__answer">
<p>Suitability for regulated use depends on your organization's quality system requirements, SOPs, validation protocols, and documentation standards — not solely on the instrument's refurbishment status. Some regulated laboratories successfully qualify and use refurbished ultracentrifuges after completing IQ/OQ/PQ protocols with appropriate documentation. Others require new instruments with full manufacturer documentation. Consult your quality assurance team to determine what documentation, calibration records, and qualification steps are required before sourcing a used unit for regulated applications. mLab Supply does not make representations about GMP or clinical suitability for any sourced instrument.</p>
</div>
</details>
<details>
<summary>What power requirements should I confirm before sourcing a floor-standing ultracentrifuge?</summary>
<div class="mlab-collection-faq__answer">
<p>Floor-standing ultracentrifuges typically require dedicated electrical circuits with specific voltage (commonly 208V or 230V single- or three-phase), amperage, and outlet configurations that differ from standard laboratory outlets. Confirm the instrument's voltage, amperage, phase, and outlet requirements before sourcing, and coordinate with your facilities team to verify that your laboratory can support the required electrical infrastructure. Failure to confirm power requirements before delivery can result in significant installation delays and additional cost.</p>
</div>
</details>
<details>
<summary>Does mLab Supply coordinate freight for floor-standing ultracentrifuges?</summary>
<div class="mlab-collection-faq__answer">
<p>Yes. Floor-standing ultracentrifuges are large, heavy instruments that require freight shipping rather than standard parcel delivery. mLab Supply can coordinate freight logistics for floor-standing systems. Freight requirements vary by instrument and destination, and may include liftgate service, inside delivery, or rigging depending on your facility. Confirm site access, loading dock availability, and any special delivery requirements when requesting a quote so we can provide accurate freight information.</p>
</div>
</details>
<details>
<summary>Does mLab Supply purchase surplus ultracentrifuges?</summary>
<div class="mlab-collection-faq__answer">
<p>Yes. mLab Supply purchases surplus and used laboratory equipment including ultracentrifuges. If your organization is decommissioning ultracentrifuge systems, contact us through the <a href="/pages/request-a-quote">Request a Quote</a> page to discuss equipment valuation and purchasing options.</p>
</div>
</details>
</div>